Reactions of Hydrolysis and Hydration
The two terms of hydrolysis and hydration both imply bond breakage with addition of a molecule of H2O. In this text, we prefer to apply the term 'hydrolysis' to the cleavage of esters (carboxylesters, lactones, inorganic esters), amides (carboxamides, sulfamates, phosphoamides, lactams, etc.), and glycosides. In contrast, the term 'hydration' will be restricted to epoxides, although the enzymes catalyzing this reaction are also classified as hydrolases (see below). Readers in search of a much more extensive treatment of hydrolases and their metabolic reactions of hydrolysis and hydration might want to consult a recent book coauthored by this writer.5
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