Flow Chart For Tuberculosis

"TUBERCULOSIS

Mycobacterium tuberajbsis \

Droplet nuclei in air currents

Inhalation into respiratory tract Organisms deposited in lung periphery

Inflammatory response Polymorphonuclear leukocytes accumulate

Polymorphonuclear leukocytes replaced by macrophages that engulf bacteria

Formation of g ia nt g ra nu la r eel Is that surround foreign cells

Necrosis within giant cell \

Calcification of lesion Formation of granuloma (tubercle)

Scar tissue encapsulates tubercle to separate it from body

Death of microorganisms

Sensitization of T lymphocytes Positive tuberculin skin test

Bacilli spread throughout lung Caseous necrosis

Clinical tuberculosis

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